Transfusion and Apheresis Science
Volume 27, Issue 2 , Pages 183-186 , October 2002

Dendritic cells in vaccination therapies of malignant diseases

References 

  1. Banchereau J, Steinman RM. Dendritic cells and the control of immunity. Nature. 1998;392:245
  2. Brossart P, Goldrath AW, Butz EA, Martin S, Bevan MJ. Virus-mediated delivery of antigenic epitopes into dendritic cells as a means to induce CTL. J. Immunol. 1997;158:3270
  3. Brossart P, Bevan MJ. Presentation of exogenous protein antigens on major histocompatibility complex class I molecules by dendritic cells: pathway of presentation and regulation by cytokines. Blood. 1997;90:1594
  4. Cella M, Sallusto F, Lanzavecchia A. Origin maturation and antigen presenting function of dendritic cells. Curr. Opin. Immunol. 1997;9:10
  5. Romani N, Reider D, Heuer M, Ebner S, Kampgen E, Eibl B, et al.  Generation of mature dendritic cells from human blood. An improved method with special regard to clinical applicability. J. Immunol. Methods. 1996;196:137
  6. Brossart P, Grunebach F, Stuhler G, Reichardt VL, Mohle R, Kanz L, et al.  Generation of functional human dendritic cells from adherent peripheral blood monocytes by CD40 ligation in the absence of granulocyte-macrophage colony-stimulating factor. Blood. 1998;92:4238
  7. Albert ML, Sauter B, Bhardwaj N. Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs. Nature. 1998;392:86
  8. Cella M, Scheidegger D, Palmer-Lehmann K, Lane P, Lanzavecchia A, Alber G. Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation. J. Exp. Med. 1996;184:747
  9. Sallusto F, Lanzavecchia A, Mackay CR. Chemokines and chemokine receptors in T-cell priming and Th1/Th2-mediated responses. Immunol. Today. 1998;19:568
  10. Minev BR, Chavez FL, Dudouet BM, Mitchell MS. Synthetic insertion signal sequences enhance MHC class I presentation of a peptide from the melanoma antigen MART-1. Eur. J. Immunol. 2000;30:2115
  11. Nestle FO, Alijagic S, Gilliet M, Sun Y, Grabbe S, Dummer R, et al.  Vaccination of melanoma patients with peptide- or tumor lysate-pulsed dendritic cells. Nat. Med. 1998;4:328
  12. Brossart P, Stuhler G, Flad T, Stevanovic S, Rammensee HG, Kanz L, et al.  Her-2/neu-derived peptides are tumor-associated antigens expressed by human renal cell and colon carcinoma lines and are recognized by in vitro induced specific cytotoxic T lymphocytes. Cancer Res. 1998;58:732
  13. Brossart P, Heinrich KS, Stuhler G, Behnke L, Reichardt VL, Stevanovic S, et al.  Identification of HLA-A2-restricted T-cell epitopes derived from the MUC1 tumor antigen for broadly applicable vaccine therapies. Blood. 1999;93:4309
  14. van der BP, Szikora JP, Boel P, Wildmann C, Somville M, Sensi M, et al.  Autologous cytolytic T lymphocytes recognize a MAGE-1 nonapeptide on melanomas expressing HLA-Cw*1601. Eur. J. Immunol. 1994;24:2134
  15. Wolfel T, Van Pel A, Brichard V, Schneider J, Seliger B, Meyer zum Buschenfelde KH, et al.  Two tyrosinase nonapeptides recognized on HLA-A2 melanomas by autologous cytolytic T lymphocytes. Eur. J. Immunol. 1994;24:759
  16. Gaugler B, Van den EB, van der BP, Romero P, Gaforio JJ, De Plaen E, et al.  Human gene MAGE-3 codes for an antigen recognized on a melanoma by autologous cytolytic T lymphocytes. J. Exp. Med. 1994;179:921
  17. Reeves ME, Royal RE, Lam JS, Rosenberg SA, Hwu P. Retroviral transduction of human dendritic cells with a tumor-associated antigen gene. Cancer Res. 1996;56:5672
  18. Nair SK, Boczkowski D, Morse M, Cumming RI, Lyerly HK, Gilboa E. Induction of primary carcinoembryonic antigen (CEA)-specific cytotoxic T lymphocytes in vitro using human dendritic cells transfected with RNA. Nat. Biotechnol. 1998;16:364
  19. Kugler A, Stuhler G, Walden P, Zoller G, Zobywalski A, Brossart P, et al.  Regression of human metastatic renal cell carcinoma after vaccination with tumor cell-dendritic cell hybrids. [see comments] Nat. Med. 2000;6:332
  20. Eibl B, Ebner S, Duba C, Bock G, Romani N, Erdel M, et al.  Dendritic cells generated from blood precursors of chronic myelogenous leukemia patients carry the Philadelphia translocation and can induce a CML-specific primary cytotoxic T-cell response. Genes Chromosomes Cancer. 1997;20:215
  21. Choudhury BA, Liang JC, Thomas EK, Flores-Romo L, Xie QS, Agusala K, et al.  Dendritic cells derived in vitro from acute myelogenous leukemia cells stimulate autologous antileukemic T-cell responses. Blood. 1999;93:780
  22. Thurner B, Haendle I, Roder C, Dieckmann D, Keikavoussi P, Jonuleit H, et al.  Vaccination with mage-3A1 peptide-pulsed mature, monocyte-derived dendritic cells expands specific cytotoxic T cells and induces regression of some metastases in advanced stage IV melanoma. J. Exp. Med. 1999;190:1669
  23. Mackensen A, Herbst B, Chen JL, Kohler G, Noppen C, Herr W, et al.  Phase I study in melanoma patients of a vaccine with peptide-pulsed dendritic cells generated in vitro from CD34(+) hematopoietic progenitor cells. Int. J. Cancer. 2000;86:385
  24. Murphy GP, Tjoa BA, Simmons SJ, Jarisch J, Bowes VA, Ragde H, et al.  Infusion of dendritic cells pulsed with HLA-A2-specific prostate-specific membrane antigen peptides: a phase II prostate cancer vaccine trial involving patients with hormone-refractory metastatic disease. Prostate. 1999;38:73
  25. Brossart P, Wirths S, Stuhler G, Reichardt VL, Kanz L, Brugger W. Induction of cytotoxic T-lymphocyte responses in vivo after vaccinations with peptide-pulsed dendritic cells. Blood. 2000;96:3102
  26. Reichardt VL, Okada CY, Liso A, Benike CJ, Stockerl-Goldstein KE, Engleman EG, et al.  Idiotype vaccination using dendritic cells after autologous peripheral blood stem cell transplantation for multiple myeloma––a feasibility study. Blood. 1999;93:2411
  27. Hsu FJ, Benike C, Fagnoni F, Liles TM, Czerwinski D, Taidi B, et al.  Vaccination of patients with B-cell lymphoma using autologous antigen-pulsed dendritic cells. Nat. Med. 1996;2:52

PII: S1473-0502(02)00041-1

Transfusion and Apheresis Science
Volume 27, Issue 2 , Pages 183-186 , October 2002

Article Tools