Transfusion and Apheresis Science
Volume 28, Issue 1 , Pages 13-18 , February 2003

Plasmapheresis therapy in pemphigus vulgaris and bullous pemphigoid

  • Gustavo Mazzi

      Affiliations

    • Servizio Immunotrasfusionale, Azienda Ospedaliera “S. Maria degli Angeli”, Via Montereale 24, 33170 Pordenone, Italy
    • Corresponding Author InformationCorresponding author. Tel.: +39-434-399273; fax: +39-434-399667
    • ,
  • Antonino Raineri

      Affiliations

    • Servizio Immunotrasfusionale, Azienda Ospedaliera “S. Maria degli Angeli”, Via Montereale 24, 33170 Pordenone, Italy
    • ,
  • Francesco Angelo Zanolli

      Affiliations

    • Servizio Immunotrasfusionale, Azienda Ospedaliera “S. Maria degli Angeli”, Via Montereale 24, 33170 Pordenone, Italy
    • ,
  • Claudio Da Ponte

      Affiliations

    • Servizio Immunotrasfusionale, Azienda Ospedaliera “S. Maria degli Angeli”, Via Montereale 24, 33170 Pordenone, Italy
    • ,
  • Dina De Roia

      Affiliations

    • Servizio Immunotrasfusionale, Azienda Ospedaliera “S. Maria degli Angeli”, Via Montereale 24, 33170 Pordenone, Italy
    • ,
  • Liliana Santarossa

      Affiliations

    • Servizio Immunotrasfusionale, Azienda Ospedaliera “S. Maria degli Angeli”, Via Montereale 24, 33170 Pordenone, Italy
    • ,
  • Renato Guerra

      Affiliations

    • UO di Dermatologia. Azienda Ospedaliera S. Maria degli Angeli, Via Montereale 24, 33170 Pordenone, Italy
    • ,
  • Bianca Maria Orazi

      Affiliations

    • Servizio Immunotrasfusionale, Azienda Ospedaliera “S. Maria degli Angeli”, Via Montereale 24, 33170 Pordenone, Italy

Received 2 September 2002 ,Accepted 12 September 2002.

References 

  1. Nousari HC, Anhalt GJ. Pemphigus and bullous pemphigoid. Lancet. 1999;354:667–672
  2. Udey MC, Stanley JR. Pemphigus-disease of antidesmosomal autoimmunity. JAMA. 1999;282(6):572–576
  3. Sams WMJ, Jordan RE. Correlation of pemphigoid and pemphigus antibody titres with activity of disease. Br. J. Dermatol. 1971;84:7–13
  4. Ding X, Aoki V, Mascaro JM, Lopez-Swiderski A, Diaz LA, Fairley JA. Mucosal and mucocutaneous (generalized) pemphigus vulgaris show distinct antibody profiles. J. Invest. Dermatol. 1997;109:592–596
  5. Yancey KB, Egan CA. Pemphigoid: clinical, histologic, immunopathologic, and therapeutic considerations. JAMA. 2000;284:350–356
  6. Korman NJ. Bullous pemphigoid. The latest in diagnosis, prognosis and therapy. Arch. Dermatol. 1998;134:1137–1141
  7. Stanley JR. Therapy of pemphigus vulgaris. Arch. Dermatol. 1999;135:76–78
  8. Bystryn JC, Steinman NM. The adjuvant therapy of pemphigus. Arch. Dermatol. 1996;132:203–212
  9. Thivolet J, Barthelemy H, Rigot-Muller G, et al.  Effects of cyclosporin on bullous pemhigoid and pemphigus. Lancet. 1985;1:334–335
  10. Enk AH, Knop J. Mycophenolate is effective in the treatment of pemphigus vulgaris. Arch. Dermatol. 1999;135:54–56
  11. Böhm M, Beissert S, Schwarz T, Metze D, Luger T. Bullous pephigoid treated with mycophenolate mofetil. Lancet. 1997;349:541
  12. Harman KE, Black MM. High-dose intravenous immune globulin for the treatment of autoimmune blistering diseases: an evaluation of its use in 14 cases. Br. J. Dermatol. 1999;140:865–874
  13. Engineer L, Ahmed AR. Role of intravenous immunoglobulin in the treatment of bullous pemphigoid: analysis of current data. J. Am. Acad. Dermatol. 2001;44(1):83–88
  14. Cotterill JA, Barker DJ, Millard LG. Plasma exchange in the treatment of pemphigus vulgaris. Br. J. Dermatol. 1978;98(2):243
  15. Tan-Lim R, Bystryn JC. Effect of plasmapheresis therapy on circulating levels of pemphigus antibodies. J. Am. Acad. Dermatol. 1990;22:35–40
  16. Søndergaard K, Carstens J, Jørgensen J, Zachariae H. The steroid-sparing effect of long term plasmapheresi in pemphigus. Acta Derm. Venereol. 1995;75:150–152
  17. Egan CA, Meadows KP, Zone JJ. Plasmapheresis as a steroid saving procedure in bullous pemphigoid. Int. J. Dermatol. 2000;39(3):230–235
  18. Turner MS, Sutton MD, Sauder DN. The use of plasmapheresis and immunosuppression in the treatment of pemphigus vulgaris. J. Am. Acad. Dermatol. 2000;43:1058–1064
  19. Euler HH, Loffler H, Christophers E. Syncronization of plasmpheresis and pulse cyclophosphamide therapy in pemphigus vulgaris. Arch. Dermatol. 1987;123:1205–1210
  20. Rossi F, Dietrich G, Kazatchkine MD. Anti-idiotypes against autoantibodies in normal immunoglobulins: evidence for network regulation of human autoimmune responses. Immunol. Rev. 1989;110:135–149
  21. Piketty C, Mouthon L, Kazatchkine MD. Immunomodulatory effects of plasma exchange and intravenous immunoglobulin (IVIg) in autoimmune and systemic inflammatory diseases. In:  Rossi U,  Bussel A,  Valbonesi M editor. Therapeutic Haemapheresis. Milano: SIMTI; 1995;p. 127–142
  22. Stanley JR. Pathophysiology and therapy of pemphigus in the 21st century. J. Dermatol. 2001;28:645–646

PII: S1473-0502(02)00095-2

doi: 10.1016/S1473-0502(02)00095-2

Transfusion and Apheresis Science
Volume 28, Issue 1 , Pages 13-18 , February 2003

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