Transfusion and Apheresis Science
Volume 28, Issue 1 , Pages 43-50 , February 2003

PUVA apoptotic response in activated and resting human lymphocytes

  • A.E Heng

      Affiliations

    • Service de Néphrologie (Pr Deteix) Henri Dunant BP69 63003, CHU Clermont-Ferrand Cedex, France
    • Corresponding Author InformationCorresponding author. Tel.: +33-4-73-75-14-25; fax: +33-4-73-75-11-83
    • ,
  • B Sauvezie

      Affiliations

    • Unité d’Immunologie Clinique et laboratoire d’Immunologie B (Pr B Sauvezie), 63003 CHU Clermont-Ferrand Cedex, France
    • ,
  • L Genestier

      Affiliations

    • INSERM U503 (Pr JP Revillard)CHU, 69000, HCL Lyon, France
    • ,
  • F Demeocq

      Affiliations

    • Unité Bioclinique (Pr F Demeocq), Departement de pédiatrie, 63003 CHU Clermont-Ferrand Cedex, France
    • ,
  • A Dosgilbert

      Affiliations

    • Unité d’Immunologie Clinique et laboratoire d’Immunologie B (Pr B Sauvezie), 63003 CHU Clermont-Ferrand Cedex, France
    • ,
  • P Deteix

      Affiliations

    • Service de Néphrologie (Pr Deteix) Henri Dunant BP69 63003, CHU Clermont-Ferrand Cedex, France

References 

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  3. Dall’Amico R, Murer L. Extracorporeal photochemotherapy: a new therapeutic approach for allograft rejection. Transfus. Apher. Sci. 2002;26(3):197–204
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  8. Yoo EK, Rook AH, Elenitsas R, Gasparro FP, Vowels BR. Apoptosis induction of ultraviolet light A and photochemotherapy in cutaneous T-cell Lymphoma: relevance to mechanism of therapeutic action. J. Invest. Dermatol. 1996;107(2):235–242
  9. Marks DI, Fox RM. Mechanisms of photochemotherapy-induced apoptotic cell death in lymphoid cells. Biochem. Cell Biol. 1991;69(10–11):754–760
  10. Vowels BR, Yoo EK, Gasparro FP. Kinetic analysis of apoptosis induction in human cell lines by UVA and 8-MOP. Photochem. Photobiol. 1996;63(5):572–576
  11. Enomoto DN, Schellekens PT, Yong SL, Ten Berge IJ, Mekkes JR, Boss JD. Extracorporeal photochemotherapy (photopheresis) induces apoptosis in lymphocytes: a possible mechanism of action of PUVA therapy. Photochem. Photobiol. 1997;65(1):177–180
  12. Godar DE. UVA1 radiation triggers two different final apoptotic pathways. J. Invest. Dermatol. 1999;112(1):3–12
  13. Legitimo A, Consolini R, Di R, Stefano W, Bencivelli A, Calleri F. Evaluation of the immunomodulatory mechanisms of photochemotherapy in transplantation. Transplant. Proc. 2001;33(3):2266–2268
  14. Aringer M, Graninger WB, Smolen JS, Kiener HP, Steiner CW, Trautinger F, et al.  Photopheresis treatment enhances CD95 (fas) expression in circulating lymphocytes of patients with systemic sclerosis and induces apoptosis. Br. J. Rheumatol. 1997;36(12):1276–1282
  15. Coven TR, Walters IB, Cardinale I, Krueger JG. PUVA-induced lymphocyte apoptosis: mechanism of action in psoriasis. Photodermatol. Photoimmunol. Photomed. 1999;15(1):22–27
  16. Bladon J, Taylor PC. Extracorporeal photopheresis in cutaneous T-cell lymphoma and graft-versus-host disease induces both immediate and progressive apoptotic processes. Br. J. Dermatol. 2002;146(1):59–68
  17. Miracco C, Rubegni P, De Aloe G, D’Ascenzo G, Mazzatenta C, De S. Extracorporeal photochemotherapy induces apoptosis of infiltrating lymphoid cells in patients with mycosis fungoides in early stages. A quantitative histological study. Br. J. Dermatol. 1997;137(4):549–557
  18. Maccherini M, Diciolla F, Laghi Pasini F, Lisi G, Tanganelli P, D’Ascenzo G, et al.  Photopheresis immunomodulation after heart transplantation. Transplant. Proc. 2001;33(1–2):1591–1594
  19. Vowels BR, Cassin M, Boufal MH, Walsh LJ, Rook AH. Extracorporeal photochemotherapy induces the production of tumor necrosis factor-alpha by monocytes: implications for the treatment of cutaneous T-cell lymphoma and systemic sclerosis. J. Invest. Dermatol. 1992;98(5):686–692
  20. Gasparro FP, Dall’Amico R, Goldminz D, Simmons E, Weingold D. Molecular aspects of extracorporeal photochemotherapy. Yale. J. Biol. Med. 1989;62(6):579–593
  21. Darzynkiewicz Z, Bruno S, Del Bino G, Gorczyca W, Hotz MA, Lassota P, et al.  Features of apoptotic cells measured by flow cytometry. Cytometry. 1992;13(8):795–808
  22. Koopman G, Reutelingsperger CP, Kuijten GA, Keehnen RM, Pals ST, van Oers MH. Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis. Blood. 1994;84(5):1415–1420
  23. Gorski G, Antosz H, Gawron A. Effect of 8-methoxypsoralen in the dark on proliferation of stimulated lymphocytes. J. Pharm. Pharmacol. 1991;43(1):63–64

PII: S1473-0502(02)00099-X

doi: 10.1016/S1473-0502(02)00099-X

Transfusion and Apheresis Science
Volume 28, Issue 1 , Pages 43-50 , February 2003

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