Transfusion and Apheresis Science
Volume 36, Issue 2 , Pages 139-142 , April 2007

Rhesus immune globulin fails to prevent immunization after rhesus incompatible blood transfusion

  • Jörg Ahrens

      Affiliations

    • Department of Anesthesiology – OE8050, Hannover Medical School, Carl-Neuberg-Strasse 1, D-30623 Hannover, Germany
    • Corresponding Author InformationCorresponding author. Tel.: +49 511 532 2489; fax: +49 511 532 3642.
    • ,
  • Hans-Gert Heuft

      Affiliations

    • Department of Transfusion Medicine, Hannover Medical School, Hannover, Germany
    • ,
  • Lilia Goudeva

      Affiliations

    • Department of Transfusion Medicine, Hannover Medical School, Hannover, Germany
    • ,
  • Michael Przemeck

      Affiliations

    • Head of Department of Anesthesiology and Intensive Care, Annastift Hospital, Hannover, Germany

Received 19 July 2006 ,Accepted 31 October 2006.

References 

  1. Federal Medical Association of Germany: Leitlinien zur Therapie mit Blutkomponenten und Plasmaderivaten, Köln, Deutscher Ärzteverlag, 2003.
  2. National Blood Service . Guidelines for the blood transfusion services in the UK. 7th ed.. Norwich (UK): The Stationary Office; 2005;
  3. Nester TA, Rumsey DM, Howell CC, Gilligan DM, Drachman JG, Maier RV, et al. Prevention of immunization to D+ red blood cells with red blood cell exchange and intravenous Rh immune globulin. Transfusion. 2004;44(12):1720–1723
  4. Pollack W, Ascari WQ, Crispen JF, O’Connor RR, Ho TY. Studies on Rh prophylaxis. II. Rh immune prophylaxis after transfusion with Rh-positive blood. Transfusion. 1971;11(6):340–344
  5. Bowman HS, Mohn JF, Lambert RM. Prevention of maternal Rh immunization after accidental transfusion of D(Rh 0)-positive blood. Vox Sang. 1972;22(5):385–396
  6. Lee D, Contreras M, Robson SC, Rodeck CH, Whittle MJ. Recommendations for the use of anti-D immunoglobulin for Rh prophylaxis. British Blood Transfusion Society and the Royal College of Obstetricians and Gynaecologists. Transfus Med. 1999;9(1):93–97
  7. Laspina S, O’Riordan JM, Lawlor E, Murphy WG. Prevention of post-transfusion RhD immunization using red cell exchange and intravenous anti-D immunoglobulin. Vox Sang. 2005;89(1):49–51
  8. Branch DW, Guyman G, Scott JR. Failure to prevent rhesus immunisation with rhesus immune globulin after incompatible blood transfusion. Lancet. 1985;1(8425):393–394
  9. Thornton JG, Page C, Foote G, Arthur GR, Tovey LA, Scott JS. Efficacy and long term effects of antenatal prophylaxis with anti-D immunoglobulin. BMJ. 1989;298(6689):1671–1673
  10. MacKenzie IZ, Bowell P, Gregory H, Pratt G, Guest C, Entwistle CC. Routine antenatal Rhesus D immunoglobulin prophylaxis: the results of a prospective 10 year study. Br J Obstet Gynaecol. 1999;106(5):492–497
  11. Bowman JM, Pollock JM. Failures of intravenous Rh immune globulin prophylaxis: an analysis of the reasons for such failures. Transfus Med Rev. 1987;1(2):101–112

PII: S1473-0502(07)00021-3

doi: 10.1016/j.transci.2006.10.009

Transfusion and Apheresis Science
Volume 36, Issue 2 , Pages 139-142 , April 2007

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