Transfusion and Apheresis Science
Volume 42, Issue 3 , Pages 289-297 , June 2010

Quality assessment of cord blood units selected for unrelated transplantation: A Transplant Center perspective

  • Alessandra Picardi

      Affiliations

    • Corresponding Author InformationCorrespondence to: Alessandra Picardi, Stem Cell Transplant Unit, Policlinico Tor Vergata, Viale Oxford n° 81, Rome, Italy. Tel.: +39 06 20903179; fax: +39 06 20903157.
  • ,
  • William Arcese

References 

  1. Gluckman E, Rocha V. Cord blood transplantation: state of the art. Haematologica. 2009;94:451–454
  2. Navarrete C, Contreras M. Cord blood banking: a historical perspective. Br J Haematol. 2009;147:236–245
  3. Brunstein CG, Barker JN, Weisdorf DJ, Defor TE, McKenna D, Chong SY, et al. Intra-BM injection to enhance engraftment after myeloablative umbilical cord blood transplantation with two partially HLA-matched units. Bone Marrow Transplant. 2009;43:935–940
  4. de Lima M, McMannis J, Gee A, Komanduri K, Couriel D, Andersson BS, et al. Transplantation of ex vivo expanded cord blood cells using the copper chelator tetraethylenepentamine: a phase I/II clinical trial. Bone Marrow Transplant. 2008;41:771–778
  5. Hiwase SD, Dyson PG, To LB, Lewis ID. Cotransplantation of placental mesenchymal stromal cells enhances single and double cord blood engraftment in nonobese diabetic/severe combined immune deficient mice. Stem Cells. 2009;27:2293–2300
  6. Verneris MR, Brunstein CG, Barker J, Macmillan ML, Defor T, McKenna DH, et al. Relapse risk after umbilical cord blood transplantation: enhanced graft versus leukemia effect in recipients of 2 units. Blood. 2009;114:3980–3981
  7. Lecchi L, Perego L, Garcea F, Ratti I, Brasca M, Dotti D, et al. Ten-year quality control of a semiautomated procedure of cord blood unit volume reduction. Transfusion. 2009;49:563–569
  8. Lapierre V, Pellegrini N, Bardey I, Malugani C, Saas P, Garnache F, et al. Cord blood volume reduction using an automated system (Sepax) vs. a semi-automated system (Optipress II) and a manual method (hydroxyethyl starch sedimentation) for routine cord blood banking: a comparative study. Cytotherapy. 2007;9:165–169
  9. Cord blood collection, processing, testing, banking, selection and release. Accreditation Manual Fact/Netcord, 3rd ed. Version 3.1; December 2008.
  10. International standards for cellular therapy product collection, processing and administration accreditation manual FACT/Netcord-Jacie, 4th ed. Version 4.1, July 2009.
  11. Warkentin PI. Voluntary accreditation of cellular therapies: foundation for the Accreditation of Cellular Therapy (FACT/NETCORD). Cytotherapy. 2003;5:299–305
  12. Wagner JE, Barker JN, De For TE, Baker KS, Blazar BR, Eide C, et al. Transplantation of unrelated donor umbilical cord blood in 102 patients with malignant and non malignant diseases: influence of CD34 cell dose and HLA disparity on the treatment related mortality and survival. Blood. 2002;100:1611–1618
  13. Laughlin MJ, Barker J, Bambach B, Koc ON, Rizzieri DA, Wagner JE, et al. Hematopoietic engraftment and survival in adult recipients of umbilical-cord blood from unrelated donors. N Engl J Med. 2001;344:1815–1822
  14. Larghero J, Rea D, Brossard Y, Van Nifterik J, Delasser V, Robert I, et al. Prospective flow cytometric evaluation of nucleated red blood cells in cord blood units and relationship with nucleated and CD34+ cell quantification. Transfusion. 2006;46:403–406
  15. Stevens CE, Gladstone J, Taylor PE, Scaradavou A, Migliaccio AR, Visser J, et al. Placental/umbilical cord blood for unrelated bone marrow reconstitution: relevance of nucleated red blood cells. Blood. 2002;100:2662–2664
  16. Van Haute I, Lootens N, De Smet S, De Buck C, Verdegem L, Vanheusden K, et al. Viable CD34+ stem cell content of a cord blood graft: which measurement performed before transplant is most representative?. Transfusion. 2004;44:547–554
  17. Picardi A, Spagnoli A, Caniglia M, Pinto R, Dentamaro T, Mangione I, et al. Quality controls of cord blood units according to JACIE standards are highly predictive in unrelated cord blood transplants. Bone Marrow Transplant. 2009;S1:P495
  18. Migliaccio AR, Adamson JW, Stevens CE, Dobrila NL, Carrier CM, Rubinstein P. Cell dose and speed of engraftment in placental/umbilical cord blood transplantation: graft progenitor cell content is a better predictor than nucleated cell quantity. Blood. 2000;96:2717–2722
  19. Goodwin HS, Gruzinger LM, Regan DM, McCormick KA, Johnson CE, Oliver DA, et al. Long term cryostorage of UC blood units: ability of the integral segment confirm both the identity and hematopoietic potential. Cytotherapy. 2003;5:80–86
  20. Iori AP, Cerretti R, De Felice L, Screnci M, Mengarelli A, Romano A, et al. Pre-transplant prognostic Fact/Netcordors for patients with high-risk leukemia undergoing an unrelated cord blood transplantation. Bone Marrow Transplant. 2004;33:1097–1105
  21. Rodrigueez L, Garcia J, Querol S. Predictive utility of the attached segment in the quality control of a cord blood graft. Biol Blood Marrow. 2005;11:247–251
  22. Kogler G, Enczmann J, Rocha V, Gluckman E, Wernet P. High-resolution HLA typing by sequencing for HLA-A, -B, -C, -DR, -DQ in 122 unrelated cord blood/patient pair transplants hardly improves long-term clinical outcome. Bone Marrow Transplant. 2005;36:1033–1041
  23. Gluckman E, Rocha V, Arcese W, Michel G, Sanz G, Chan KW, et al. Fact/Netcordors associated with outcomes of unrelated cord blood transplant: guidelines for donor choice. Exp Hematol. 2004;32:397–407
  24. Willemze R, Rodrigues CA, Labopin M, Sanz G, Michel G, Socié G, et al. KIR-ligand incompatibility in the graft-versus-host direction improves outcomes after umbilical cord blood transplantation for acute leukemia. Leukemia. 2009;23:492–500
  25. McCullogh J, McKenna D, Kadidlo D, Maurer D, Noreen HJ, French K, et al. Mislabeled units of umbilical cord blood detected by a quality assurance program at the transplant center. Blood. 2009;114:1684–1688
  26. Tomonari A, Takahashi S, Konuma T, Kobayashi T, Sato A, Iseki T, et al. Impact of ABO incompatibility on engraftment and transfusion requirement after unrelated cord blood transplantation: a single institute experience in Japan. Bone Marrow Transplant. 2007;40:523–528
  27. Anstee DJ. Red cell genotyping and the future of pre-transfusion testing. Blood. 2009;114:248–256
  28. Westhoff CM. Molecular testing for transfusion medicine. Curr Opin Hematol. 2006;13:471–475
  29. Thyagarajan B, Berger M, Sumstad D, McKenna DH. Loss of integrity of umbilical cord blood unit freezing bags: description and consequences. Transfusion. 2008;48:1138–1142
  30. McCullogh J, Mckenna D, Kadidlo D, Schierman T, Wagner J. Issues in the quality of umbilical cord blood stem cells for transplantation. Transfusion. 2005;45:832–841
  31. Wagner E, Duval M, Dalle JH, Morin H, Bizier S, Champagne J. Champagne MA Assessment of cord blood unit characteristics on the day of transplant: comparison with data issued by cord blood banks. Transfusion. 2006;46:1190–1198

PII: S1473-0502(10)00056-X

doi: 10.1016/j.transci.2010.03.004

Transfusion and Apheresis Science
Volume 42, Issue 3 , Pages 289-297 , June 2010