Abstract
ABO antibodies occur naturally and usually exist as alloantibodies. They are the most
clinically significant in cases of transfusions. However, there are very few reports
on auto-anti-A or B. A 58-year-old man visited our hospital for evaluation of an inguinal
mass. Blood typing was performed, while preparing the patient for an excisional biopsy.
Forward and reverse typing showed a typical AB and A pattern. Results of the direct
antiglobulin and unexpected antibody screening tests were negative. The serum did
not react with AB3 cells. The biopsy revealed a diffuse large B-cell lymphoma. After
completing four cycles of R-CHOP chemotherapy, the patient achieved complete remission.
There were no anti-B antibodies found on repeat ABO typing. This report shares our
experience on unexpected anti-B antibody findings in a patient with an A1B blood type.
To the best of our knowledge, this is the first report of anti-B antibodies in a patient
with an A1B blood type in Korea.
Keywords
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Article info
Publication history
Published online: April 20, 2022
Accepted:
April 17,
2022
Received in revised form:
April 12,
2022
Received:
January 23,
2022
Identification
Copyright
© 2022 Elsevier Ltd. All rights reserved.
