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Analysis and clinical significance of peripheral blood routine changes of platelet donors with ultra-high frequency donation

  • Xin Zhao
    Correspondence
    Correspondence to: Hainan Provincial Blood Center, 16 Meisu Road, Haikou 570311, Hainan Province, China.
    Affiliations
    Department of Blood Examination and Collection, Hainan Provincial Blood Center, Haikou 570311, Hainan Province, China
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  • Haoyi Qin
    Affiliations
    Department of Blood Examination and Collection, Hainan Provincial Blood Center, Haikou 570311, Hainan Province, China
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  • Wenhao Chen
    Affiliations
    Department of Blood Examination and Collection, Hainan Provincial Blood Center, Haikou 570311, Hainan Province, China
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  • Xiujuan Dong
    Correspondence
    Correspondence to: Hainan Women and Children’s Medical Center, Changbin Road, Haikou 570312, Hainan Province, China.
    Affiliations
    Department of Hematology Oncology, Hainan Women and Children’s Medical Center, Haikou 570312, Hainan Province, China
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Published:November 18, 2022DOI:https://doi.org/10.1016/j.transci.2022.103604

      Abstract

      Background

      Increasing platelet donation frequency has become an important way to meet the growing clinical platelet need. Accordingly, the problem of whether the increase in platelet donation times will have an adverse effect on the health of donors has attracted more and more attention, and become an important factor affecting the donor enthusiasm and the safety of blood collection and supply.

      Methods

      Eleven ultra-high frequency platelet donors who donated more than or equal to 20 times in 2021 were selected, and the main peripheral blood routine indicators of hemoglobin, platelet and hematocrit were analyzed.

      Results

      The above indicators of all donors fluctuated with the increase of donation times. Among them, older donors (≥50 years old) exhibited a significant downward trend in the above three indicators, and one young donor showed a downward trend in hemoglobin and hematocrit indicators. While the other donors showed the relatively stable performance of the above indicators.

      Conclusion

      The effect of ultra-high frequency platelet donation on the main peripheral blood indexes of donors shows obvious age compliance, that is, the potential harm to ultra-high frequency donors older than 50 years is significantly greater than that of donors of other ages. Older platelet donors should be cautious about ultra-high frequency donations to avoid adverse health hazards. Meanwhile, the work will provide technical reference for the more scientific and efficient development of the platelet harvesting work and the establishment of the clinical blood supply system for related patients.

      Keywords

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