Abstract
In 2019, the Italian National Blood Center (NBC), at the request of the Italian Scientific
Society of Haemapheresis and Cell Manipulation (SIdEM), included the Italian Registry
of Therapeutic Apheresis (IRTA) in the Information System of Transfusion Services
(SISTRA), whose activity is coordinated by the NBC.
The IRTA provides institutions and scientific societies with a wide range of information
including therapeutic procedures and outcomes of treated patients.
The Italian National Health Service offers therapeutic apheresis for patients with
various conditions, but it is mainly the patient with haematological and/or neurological
disorders who turns to the apheresis centres as evidenced by the activity data of
2021. In the haematological field, the apheresis centres mainly supply haematopoietic
stem cells for autologous or allogeneic transplantation as well as mononuclear cell
collection for extracorporeal photopheresis (ECP), a therapeutic approach of II line
in post-transplant Graft versus Host Disease.
The activity of 2021 in the neurological field confirms the data of 2019, the pre-pandemic
year, and indicates that myasthenia, chronic inflammatory demyelinating polyneuropathy
and Guillain-Barré syndrome along with other neurological pathologies related to immune
disorders are the diseases in which apheresis procedures are most used.
In conclusion, the IRTA is a valuable tool for monitoring the activity of apheresis
centres carried out at a national level and above all for providing an overall picture
of how the use of this therapeutic tool evolves and changes over time.
Keywords
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References
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Article info
Publication history
Published online: February 06, 2023
Accepted:
February 5,
2023
Received in revised form:
January 25,
2023
Received:
December 20,
2022
Publication stage
In Press Journal Pre-ProofIdentification
Copyright
© 2023 Elsevier Ltd. All rights reserved.
